GlycoNAVI: CheGly (Chemical Glycosylation)
ACT

Rebeccamycin

ID Compound Name Target Name Species Assay Method Activity Value Conditions DOI
act634RebeccamycinP388 leukemiaDay 1\nDose (mg/kg/injection)\nEffect MST % T/C  512 15510.7164/antibiotics.40.668
act635RebeccamycinP388 leukemiaDay 1\nDose (mg/kg/injection)\nEffect MST % T/C 256 13610.7164/antibiotics.40.668
act636RebeccamycinP388 leukemiaDay 1\nDose (mg/kg/injection)\nEffect MST % T/C 128 13210.7164/antibiotics.40.668
act637RebeccamycinP388 leukemiaDay 1\nDose (mg/kg/injection)\nEffect MST % T/C 64 13610.7164/antibiotics.40.668
act638RebeccamycinP388 leukemiaDay 1\nDose (mg/kg/injection)\nEffect MST % T/C 32 11810.7164/antibiotics.40.668
act639RebeccamycinP388 leukemiaDay 1\nDose (mg/kg/injection)\nEffect MST % T/C 16 13610.7164/antibiotics.40.668
act640RebeccamycinP388 leukemiaQ4D, days 1, 5, 9\nDose (mg/kg/injection)\nEffect MST % T/C 256 14110.7164/antibiotics.40.668
act641RebeccamycinP388 leukemiaQ4D, days 1, 5, 9\nDose (mg/kg/injection)\nEffect MST % T/C 128 14510.7164/antibiotics.40.668
act642RebeccamycinP388 leukemiaQ4D, days 1, 5, 9\nDose (mg/kg/injection)\nEffect MST % T/C 64 15010.7164/antibiotics.40.668
act643RebeccamycinP388 leukemiaQ4D, days 1, 5, 9\nDose (mg/kg/injection)\nEffect MST % T/C 32 13610.7164/antibiotics.40.668
act644RebeccamycinP388 leukemiaQ4D, days 1, 5, 9\nDose (mg/kg/injection)\nEffect MST % T/C 16 12310.7164/antibiotics.40.668
act645RebeccamycinP388 leukemiaQ4D, days 1, 5, 9\nDose (mg/kg/injection)\nEffect MST % T/C 8 14110.7164/antibiotics.40.668
act646RebeccamycinP388 leukemiaQD 1 to 5 days\nDose (mg/kg/injection)\nEffect MST % T/C 256 15010.7164/antibiotics.40.668
act647RebeccamycinP388 leukemiaQD 1 to 5 days\nDose (mg/kg/injection)\nEffect MST % T/C 128 16810.7164/antibiotics.40.668
act648RebeccamycinP388 leukemiaQD 1 to 5 days\nDose (mg/kg/injection)\nEffect MST % T/C 64 12710.7164/antibiotics.40.668
act649RebeccamycinP388 leukemiaQD 1 to 5 days\nDose (mg/kg/injection)\nEffect MST % T/C 32 14510.7164/antibiotics.40.668
act650RebeccamycinP388 leukemiaQD 1 to 5 days\nDose (mg/kg/injection)\nEffect MST % T/C 16 14510.7164/antibiotics.40.668
act651RebeccamycinP388 leukemiaQD 1 to 5 days\nDose (mg/kg/injection)\nEffect MST % T/C 8 14110.7164/antibiotics.40.668
act652RebeccamycinL1210 leukemiaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 256 17510.7164/antibiotics.40.668
act653RebeccamycinL1210 leukemiaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 128 16710.7164/antibiotics.40.668
act654RebeccamycinL1210 leukemiaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 64 14210.7164/antibiotics.40.668
act655RebeccamycinL1210 leukemiaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 32 13310.7164/antibiotics.40.668
act656RebeccamycinL1210 leukemiaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 16 13310.7164/antibiotics.40.668
act657RebeccamycinL1210 leukemiaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 8 12510.7164/antibiotics.40.668
act658RebeccamycinL1210 leukemiaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 4 11710.7164/antibiotics.40.668
act659RebeccamycinL1210 leukemiaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 2 10010.7164/antibiotics.40.668
act660RebeccamycinB16 melanomaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 256 15010.7164/antibiotics.40.668
act661RebeccamycinB16 melanomaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 128 15010.7164/antibiotics.40.668
act662RebeccamycinB16 melanomaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 64 14710.7164/antibiotics.40.668
act663RebeccamycinB16 melanomaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 32 13310.7164/antibiotics.40.668
act664RebeccamycinB16 melanomaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 16 13110.7164/antibiotics.40.668
act665RebeccamycinB16 melanomaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 8 11410.7164/antibiotics.40.668
act666RebeccamycinB16 melanomaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 4 11110.7164/antibiotics.40.668
act667RebeccamycinB16 melanomaip, QD 1 to 9 days\nDose (mg/kg/injection)\nEffect MST % T/C 2 10610.7164/antibiotics.40.668
act668RebeccamycinDNADrug concentration (µg/ml)\n1\n10\n100  96 87 5710.7164/antibiotics.40.668
act669RebeccamycinRNADrug concentration (µg/ml)\n1\n10\n100  95 88 8410.7164/antibiotics.40.668
act670RebeccamycinproteinDrug concentration (µg/ml)\n1\n10\n100 87 76 8710.7164/antibiotics.40.668
act671RebeccamycinCalculated frequency for single-strand DNAbreakageDrug concentration (µg/ml)\n0.1\n0.3\n1.0\n3.0\n10.0Breaks/10^8 nucleosides 0.5 1.8 11.9 74.0 316.410.7164/antibiotics.40.668
act672RebeccamycinA549   \nDMSO µg/ml\nDMSO % (vol/vol) at end point\nDMSO % (vol/vol) controlIC50 1.2 (0.015) 2.310.7164/antibiotics.40.668
act673RebeccamycinB16-F10\nDMSO µg/ml\nDMSO % (vol/vol) at end point\nDMSO % (vol/vol) controlIC50 0.48 (0.006) 4.010.7164/antibiotics.40.668
act674RebeccamycinHCT-116\nDMSO µg/ml\nDMSO % (vol/vol) at end point\nDMSO % (vol/vol) controlIC50 0.41 (0.005) 3.810.7164/antibiotics.40.668
act675RebeccamycinKB\nDMSO µg/ml\nDMSO % (vol/vol) at end point\nDMSO % (vol/vol) controlIC50 16.4 (0.2) 4.710.7164/antibiotics.40.668
act676RebeccamycinMOSER\nDMSO µg/ml\nDMSO % (vol/vol) at end point\nDMSO % (vol/vol) controlIC50 98.0 (1.2) 3.410.7164/antibiotics.40.668
act677RebeccamycinM109\nDMSO µg/ml\nDMSO % (vol/vol) at end point\nDMSO % (vol/vol) controlIC50 27.9 (0.35) 3.810.7164/antibiotics.40.668
act678RebeccamycinStaphylococcus aureus A9537MIC (μg/ml)110.7164/antibiotics.40.668
act679RebeccamycinStreptococcus faecalis A2068 8MIC (μg/ml)810.7164/antibiotics.40.668
act680RebeccamycinEscherichia coli A15119MIC (μg/ml)>12510.7164/antibiotics.40.668
act681RebeccamycinKlebsiella pneumoniae A9664MIC (μg/ml)>12510.7164/antibiotics.40.668
act682RebeccamycinPseudomonas aeruginosa A9843aMIC (μg/ml)>12510.7164/antibiotics.40.668
act683RebeccamycinProteus mirabilis A9900MIC (μg/ml)>12510.7164/antibiotics.40.668
act684RebeccamycinCandida albicans A9540MIC (μg/ml)>3210.7164/antibiotics.40.668
act685RebeccamycinC. albicans A15049MIC (μg/ml)>3210.7164/antibiotics.40.668
act686RebeccamycinC. krusei A10502MIC (μg/ml)>3210.7164/antibiotics.40.668
act687RebeccamycinC. krusei A22492MIC (μg/ml)>3210.7164/antibiotics.40.668
act688RebeccamycinC. tropicalis A15051MIC (μg/ml)>3210.7164/antibiotics.40.668
act689RebeccamycinC. tropicalis A22493MIC (μg/ml)>3210.7164/antibiotics.40.668
act690RebeccamycinTrichophyton tonsurans A22833MIC (μg/ml)>3210.7164/antibiotics.40.668
act691RebeccamycinT. rubrum A22789MIC (μg/ml)>3210.7164/antibiotics.40.668
act692RebeccamycinMicrosporum gypseum A22810MIC (μg/ml)>3210.7164/antibiotics.40.668
act693RebeccamycinM. canis A9872MIC (μg/ml)>3210.7164/antibiotics.40.668
act694RebeccamycinM. canis A22494MIC (μg/ml)>3210.7164/antibiotics.40.668