GlycoNAVI: CheGly (Chemical Glycosylation)
ACT

Trioxacarcin A

ID Compound Name Target Name Species Assay Method Activity Value Conditions DOI
act775Trioxacarcin AStaphylococcus aureus ATCC 6538PMIC (μg/ml)0.210.7164/antibiotics.34.1525
act778Trioxacarcin ABacillus subtilis No. 10707MIC (μg/ml)0.0110.7164/antibiotics.34.1525
act781Trioxacarcin AKlebsiella pneumoniae ATCC 10031MIC (μg/ml)1.510.7164/antibiotics.34.1525
act784Trioxacarcin ASalmonella typhosa ATCC 9992MIC (μg/ml)5010.7164/antibiotics.34.1525
act787Trioxacarcin AEscherichia coli ATCC 26MIC (μg/ml)1210.7164/antibiotics.34.1525
act790Trioxacarcin Amurine sarcoma 180 (s.c. - i.p.)Dose (mg/kg)\nTumor volume (mm3)\nT/C0.2 775 0.5510.7164/antibiotics.34.1525
act791Trioxacarcin Amurine sarcoma 180 (s.c. - i.p.)Dose (mg/kg)\nTumor volume (mm3)\nT/C0.1 930 0.6610.7164/antibiotics.34.1525
act792Trioxacarcin Amurine sarcoma 180 (s.c. - i.p.)Dose (mg/kg)\nTumor volume (mm3)\nT/C0.2 x 7 592 0.4210.7164/antibiotics.34.1525
act793Trioxacarcin Amurine sarcoma 180 (s.c. - i.p.)Dose (mg/kg)\nTumor volume (mm3)\nT/C0.1 x 7 846 0.6010.7164/antibiotics.34.1525
act799Trioxacarcin Amurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)0.4 12.4 1810.7164/antibiotics.34.1525
act800Trioxacarcin Amurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)0.3 13.4 2810.7164/antibiotics.34.1525
act801Trioxacarcin Amurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)0.2 12.6 2010.7164/antibiotics.34.1525
act802Trioxacarcin Amurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)0.1 12.9 2310.7164/antibiotics.34.1525
act803Trioxacarcin Amurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)0.15 x 5 12.6 2010.7164/antibiotics.34.1525
act804Trioxacarcin Amurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)0.10 x 5 14.8 3510.7164/antibiotics.34.1525
act805Trioxacarcin Amurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)0.05 13.4 2810.7164/antibiotics.34.1525
act813Trioxacarcin AEscherichia coliBacteriaagar diffusion test with 30-40μg/paper disk (9mmφ), \ndiameter of inhibition zones in [mm]3410.7164/antibiotics.34.1525
act818Trioxacarcin ABacillus subtilisBacteriaagar diffusion test with 30-40μg/paper disk (9mmφ), \ndiameter of inhibition zones in [mm]4010.7164/antibiotics.34.1525
act823Trioxacarcin AStaphylococcus viridochromogenes Tu 57Bacteriaagar diffusion test with 30-40μg/paper disk (9mmφ), \ndiameter of inhibition zones in [mm]2510.7164/antibiotics.34.1525
act828Trioxacarcin AStaphylococcus aureusBacteriaagar diffusion test with 30-40μg/paper disk (9mmφ), \ndiameter of inhibition zones in [mm]2410.7164/antibiotics.34.1525
act833Trioxacarcin APlasmodium falciparumPlasmodiumIC50 K1\nIC50 NF541.6±0.1 1.5±0.110.7164/antibiotics.34.1525
act837Trioxacarcin AHT-29TumorIC70 values (μg/ml)<0.310.7164/antibiotics.34.1525
act841Trioxacarcin ASF-268TumorIC70 values (μg/ml)<0.000310.7164/antibiotics.34.1525
act845Trioxacarcin AH-460TumorIC70 values (μg/ml)<0.000310.7164/antibiotics.34.1525
act849Trioxacarcin ALXFA 526LTumorIC70 values (μg/ml)<0.310.7164/antibiotics.34.1525
act853Trioxacarcin ALXFL 529LTumorIC70 values (μg/ml)<0.000310.7164/antibiotics.34.1525
act857Trioxacarcin AMCF-7TumorIC70 values (μg/ml)<0.000310.7164/antibiotics.34.1525
act861Trioxacarcin AMEXF 514LTumorIC70 values (μg/ml)0.00210.7164/antibiotics.34.1525
act865Trioxacarcin APC3MTumorIC70 values (μg/ml)0.00910.7164/antibiotics.34.1525
act869Trioxacarcin ARXF 631LTumorIC70 values (μg/ml)0.07210.7164/antibiotics.34.1525
act873Trioxacarcin Alarge cell lung cancer xenograft LXFL 529 in vitroTumorIC50 values (μg/ml)\nIC70 values (μg/ml)\nIC90 values (μg/ml)<0.1 0.16 0.7410.7164/antibiotics.34.1525