GlycoNAVI: CheGly (Chemical Glycosylation)
ACT

Trioxacarcin B

ID Compound Name Target Name Species Assay Method Activity Value Conditions DOI
act829Trioxacarcin BStaphylococcus aureusBacteriaagar diffusion test with 30-40μg/paper disk (9mmφ), \ndiameter of inhibition zones in [mm]2210.7164/antibiotics.34.1525
act796Trioxacarcin Bmurine sarcoma 180 (s.c. - i.p.)Dose (mg/kg)\nTumor volume (mm3)\nT/C20 1057 0.7510.7164/antibiotics.34.1525
act862Trioxacarcin BMEXF 514LTumorIC70 values (μg/ml)5.75610.7164/antibiotics.34.1525
act785Trioxacarcin BSalmonella typhosa ATCC 9992MIC (μg/ml)>10010.7164/antibiotics.34.1525
act846Trioxacarcin BH-460TumorIC70 values (μg/ml)1.4710.7164/antibiotics.34.1525
act809Trioxacarcin Bmurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)6.25 14.5 3810.7164/antibiotics.34.1525
act779Trioxacarcin BBacillus subtilis No. 10707MIC (μg/ml)1210.7164/antibiotics.34.1525
act819Trioxacarcin BBacillus subtilisBacteriaagar diffusion test with 30-40μg/paper disk (9mmφ), \ndiameter of inhibition zones in [mm]3810.7164/antibiotics.34.1525
act854Trioxacarcin BLXFL 529LTumorIC70 values (μg/ml)0.60910.7164/antibiotics.34.1525
act794Trioxacarcin Bmurine sarcoma 180 (s.c. - i.p.)Dose (mg/kg)\nTumor volume (mm3)\nT/C75 775 0.5510.7164/antibiotics.34.1525
act870Trioxacarcin BRXF 631LTumorIC70 values (μg/ml)2.14610.7164/antibiotics.34.1525
act807Trioxacarcin Bmurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)25 15.5 4810.7164/antibiotics.34.1525
act838Trioxacarcin BHT-29TumorIC70 values (μg/ml)6.46310.7164/antibiotics.34.1525
act776Trioxacarcin BStaphylococcus aureus ATCC 6538PMIC (μg/ml)5010.7164/antibiotics.34.1525
act814Trioxacarcin BEscherichia coliBacteriaagar diffusion test with 30-40μg/paper disk (9mmφ), \ndiameter of inhibition zones in [mm]3210.7164/antibiotics.34.1525
act850Trioxacarcin BLXFA 526LTumorIC70 values (μg/ml)2.47610.7164/antibiotics.34.1525
act788Trioxacarcin BEscherichia coli ATCC 26MIC (μg/ml)>10010.7164/antibiotics.34.1525
act866Trioxacarcin BPC3MTumorIC70 values (μg/ml)>3.010.7164/antibiotics.34.1525
act806Trioxacarcin Bmurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)50 17.0 6210.7164/antibiotics.34.1525
act834Trioxacarcin BPlasmodium falciparumPlasmodiumIC50 K1\nIC50 NF54102±4.9 82±6.110.7164/antibiotics.34.1525
act874Trioxacarcin Blarge cell lung cancer xenograft LXFL 529 in vitroTumorIC50 values (μg/ml)\nIC70 values (μg/ml)\nIC90 values (μg/ml)6.0 25.0 157.010.7164/antibiotics.34.1525
act824Trioxacarcin BStaphylococcus viridochromogenes Tu 57Bacteriaagar diffusion test with 30-40μg/paper disk (9mmφ), \ndiameter of inhibition zones in [mm]2710.7164/antibiotics.34.1525
act795Trioxacarcin Bmurine sarcoma 180 (s.c. - i.p.)Dose (mg/kg)\nTumor volume (mm3)\nT/C50 846 0.6010.7164/antibiotics.34.1525
act858Trioxacarcin BMCF-7TumorIC70 values (μg/ml)1.31410.7164/antibiotics.34.1525
act782Trioxacarcin BKlebsiella pneumoniae ATCC 10031MIC (μg/ml)>10010.7164/antibiotics.34.1525
act842Trioxacarcin BSF-268TumorIC70 values (μg/ml)1.47710.7164/antibiotics.34.1525
act808Trioxacarcin Bmurine leukemia P388 (i.p. - i.p.).Dose (mg/kg)\nSurvival days\nIncrease of life span (%)12.5 16.4 5610.7164/antibiotics.34.1525