GlycoNAVI: CheGly (Chemical Glycosylation)
ACT

Vineomycin A1

ID Compound Name Target Name Species Assay Method Activity Value Conditions DOI
act1985Vineomycin A1Staphylococcus aureus FDA 209PAgar dilution method, MIC (µg/ml)0.78nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act1989Vineomycin A1S. aureus FS-1227 (Penicillin resistant)Agar dilution method, MIC (µg/ml)0.39nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act1993Vineomycin A1Bacillus subtilis PCI 219Agar dilution method, MIC (µg/ml)3.12nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act1997Vineomycin A1B. cereus TAgar dilution method, MIC (µg/ml)12.5nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2001Vineomycin A1Sarcina lutea PCI 1001Agar dilution method, MIC (µg/ml)0.78nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2005Vineomycin A1Mycobacterium smeginatis ATCC 607Agar dilution method, MIC (µg/ml)>100nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2009Vineomycin A1Escherichia coli NIHJAgar dilution method, MIC (µg/ml)>100nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2013Vineomycin A1Salmonella typhimuriumAgar dilution method, MIC (µg/ml)>100nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2017Vineomycin A1Shigella sonnei E-33Agar dilution method, MIC (µg/ml)>100nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2021Vineomycin A1Pseudomonas aeruginosa P-3Agar dilution method, MIC (µg/ml)>100nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2025Vineomycin A1Candida albicansAgar dilution method, MIC (µg/ml)>100nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2029Vineomycin A1Saccharomyces sakeAgar dilution method, MIC (µg/ml)12.5nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2033Vineomycin A1Piricularia oryzaeAgar dilution method, MIC (µg/ml)25nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2037Vineomycin A1Aspergillus nigerAgar dilution method, MIC (µg/ml)>100nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2041Vineomycin A1Microsporum gypseumAgar dilution method, MIC (µg/ml)25nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2045Vineomycin A1Trichophyton interdigitaleAgar dilution method, MIC (µg/ml)100nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2049Vineomycin A1T. mentagrophytesAgar dilution method, MIC (µg/ml)100nutrient agar for bacteria (37°C, 24 hours) and glucose-potato agar for fungi (27°C, 72 hours).10.1021/ja407827n
act2053Vineomycin A1Sarcoma-180 solid (ddy mouse)Dose (mg/kg)\nTumor size (T/C)\nNo. of death\nBody weight\n change (g)\n50 0.13 0/7 -3.0Treatment: Suspension of an antibiotic in 0.3% carboxymethyl cellulose was administered intraperitoneally Single shot: 1 day after transplantation of tumor Multiple shot: 1, 2, 4, 5 and 6 day Judgement: A tumor size (ab^2/2) at 7th day after transplantation of tumor was compared with that of control: a, length; b, width.10.1021/ja407827n
act2054Vineomycin A1Sarcoma-180 solid (ddy mouse)Dose (mg/kg)\nTumor size (T/C)\nNo. of death\nBody weight\n change (g)\n100 0.31 3/7 -0.6Treatment: Suspension of an antibiotic in 0.3% carboxymethyl cellulose was administered intraperitoneally Single shot: 1 day after transplantation of tumor Multiple shot: 1, 2, 4, 5 and 6 day Judgement: A tumor size (ab^2/2) at 7th day after transplantation of tumor was compared with that of control: a, length; b, width.10.1021/ja407827n
act2055Vineomycin A1Sarcoma-180 solid (ddy mouse)Dose (mg/kg)\nTumor size (T/C)\nNo. of death\nBody weight\n change (g)\n4.4×5 0.72 0/7 -0.7Treatment: Suspension of an antibiotic in 0.3% carboxymethyl cellulose was administered intraperitoneally Single shot: 1 day after transplantation of tumor Multiple shot: 1, 2, 4, 5 and 6 day Judgement: A tumor size (ab^2/2) at 7th day after transplantation of tumor was compared with that of control: a, length; b, width.10.1021/ja407827n
act2056Vineomycin A1Sarcoma-180 solid (ddy mouse)Dose (mg/kg)\nTumor size (T/C)\nNo. of death\nBody weight\n change (g)\n6.7×5 0.38 0/7 -2.0Treatment: Suspension of an antibiotic in 0.3% carboxymethyl cellulose was administered intraperitoneally Single shot: 1 day after transplantation of tumor Multiple shot: 1, 2, 4, 5 and 6 day Judgement: A tumor size (ab^2/2) at 7th day after transplantation of tumor was compared with that of control: a, length; b, width.10.1021/ja407827n